Edward Duncan's micro allele at 464c
This letter explains why the Value for 464c was changed from 15 to 16 for Ed Duncan
From: "Bennett Greenspan"
To: "'Bennett Greenspan'"
Date: Sat, 3 Jan 2004 16:22:15 -0600
Subject: Adjustment on one marker on recent DNA data upload

Hello

Test results for the last 13 markers for your profile were uploaded Dec. 30th.

In on of your marker 464 loci your sample had what is called a micro allele.

That means that while the normal repeated sequence is like acgtacgtacgt (that is 3 repeats long--acgt time 3) However in your case instead of 3 repeats your sample had acgtacgtacg , so it was missing the t of the repeated segment. It's not common, but we see it from time to time.

In principle we have asked ourselves 'did he gain the acg or did he loose the t'. In this case the lab feels that the likelihood of you have lost the t instead of gaining 3/4 of another repeat (the acg) is very high and we round it to the next higher repeat for scoring and display purposes, in the example I gave we would call that repeat a 3 NOT a 2.

This "post Christmas batch" results came to us in the pre-rounded form, so when we uploaded the data the remainder was looped off, and in the example given above the '2' was reported.

When I complete this email I was fix the record to reflect the rounded up number rather then the looped off number.

E-mail any time.

Best Regards,

Bennett Greenspan
President
Family Tree DNA
www.FamilyTreeDNA.com

"History Unearthed Daily"


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